Perimenopause
Perimenopause is the transition phase before menopause, usually starting in the late 30s or 40s, when estrogen and progesterone begin to fluctuate. Weight gain around the middle, disrupted sleep, and mood shifts are among the most common symptoms women report.
Medically reviewed by Wasef Health. Last reviewed July 16, 2026.
Why weight changes in perimenopause
As estrogen becomes erratic, many women notice fat storage shifting toward the abdomen, stronger cravings, and a slower response to the diet and exercise habits that used to work. Declining progesterone can also disturb sleep, and short sleep is closely tied to appetite. None of this is a willpower failure; it is biology changing the rules mid-game.
How Elara can help
A licensed provider reviews your history and symptoms and may recommend hormone support such as progesterone, hormone aware GLP-1 weight care, or a gentler microdosing approach, depending on what fits your picture. Treatment is always individualized and prescribed only when appropriate.
Treatment options
- ProgesteroneA prescription hormone therapy designed to support sexual wellness by restoring progesterone levels and promoting hormonal balance. May help support libido, mood, sleep, and overall sexual well-being during periods of hormonal change.
- Semaglutide GLP-1 InjectionsPersonalized compounded semaglutide (GLP-1) care for women, prescribed when you qualify.
- Tirzepatide GLP-1/GIP InjectionsPersonalized compounded tirzepatide (GLP-1 and GIP) care for women, prescribed when you qualify.
- GLP-1 MicrodosingLow-dose GLP-1 care tailored to your individual wellness plan.
Frequently asked questions
How do I know I am in perimenopause?
Common signs include cycle changes, sleep disruption, night sweats, mood shifts, and new weight gain around the middle, typically in your 40s. A licensed provider can review your symptoms and history to help you understand where you are.
Can GLP-1 medications help with perimenopausal weight gain?
For many women, yes, when prescribed appropriately. GLP-1s quiet appetite signals while your provider addresses the hormonal side of the picture. Your provider decides whether they are right for you.
Do I have to choose between hormone support and weight care?
No. Because both live on one platform at Elara, your provider can consider them together and build a plan that fits, rather than treating each symptom separately.